#define VEC4_ROT(A, IMM) \
    _mm_or_si128(_mm_slli_epi32(A, IMM), _mm_srli_epi32(A, (32 - IMM)))

/* same, but replace 2 of the shift/shift/or "rotation" by byte shuffles (8 &
 * 16) (better) */
#define VEC4_QUARTERROUND_SHUFFLE(A, B, C, D) \
    x_##A = _mm_add_epi32(x_##A, x_##B);      \
    t_##A = _mm_xor_si128(x_##D, x_##A);      \
    x_##D = _mm_shuffle_epi8(t_##A, rot16);   \
    x_##C = _mm_add_epi32(x_##C, x_##D);      \
    t_##C = _mm_xor_si128(x_##B, x_##C);      \
    x_##B = VEC4_ROT(t_##C, 12);              \
    x_##A = _mm_add_epi32(x_##A, x_##B);      \
    t_##A = _mm_xor_si128(x_##D, x_##A);      \
    x_##D = _mm_shuffle_epi8(t_##A, rot8);    \
    x_##C = _mm_add_epi32(x_##C, x_##D);      \
    t_##C = _mm_xor_si128(x_##B, x_##C);      \
    x_##B = VEC4_ROT(t_##C, 7)

#define VEC4_QUARTERROUND(A, B, C, D) VEC4_QUARTERROUND_SHUFFLE(A, B, C, D)

if (bytes >= 256) {
    /* constant for shuffling bytes (replacing multiple-of-8 rotates) */
    __m128i rot16 =
        _mm_set_epi8(13, 12, 15, 14, 9, 8, 11, 10, 5, 4, 7, 6, 1, 0, 3, 2);
    __m128i rot8 =
        _mm_set_epi8(14, 13, 12, 15, 10, 9, 8, 11, 6, 5, 4, 7, 2, 1, 0, 3);

    __m128i x_0  = _mm_set1_epi32(x[0]);
    __m128i x_1  = _mm_set1_epi32(x[1]);
    __m128i x_2  = _mm_set1_epi32(x[2]);
    __m128i x_3  = _mm_set1_epi32(x[3]);
    __m128i x_4  = _mm_set1_epi32(x[4]);
    __m128i x_5  = _mm_set1_epi32(x[5]);
    __m128i x_6  = _mm_set1_epi32(x[6]);
    __m128i x_7  = _mm_set1_epi32(x[7]);
    __m128i x_8  = _mm_set1_epi32(x[8]);
    __m128i x_9  = _mm_set1_epi32(x[9]);
    __m128i x_10 = _mm_set1_epi32(x[10]);
    __m128i x_11 = _mm_set1_epi32(x[11]);
    __m128i x_12;
    __m128i x_13;
    __m128i x_14   = _mm_set1_epi32(x[14]);
    __m128i x_15   = _mm_set1_epi32(x[15]);
    __m128i orig0  = x_0;
    __m128i orig1  = x_1;
    __m128i orig2  = x_2;
    __m128i orig3  = x_3;
    __m128i orig4  = x_4;
    __m128i orig5  = x_5;
    __m128i orig6  = x_6;
    __m128i orig7  = x_7;
    __m128i orig8  = x_8;
    __m128i orig9  = x_9;
    __m128i orig10 = x_10;
    __m128i orig11 = x_11;
    __m128i orig12;
    __m128i orig13;
    __m128i orig14 = x_14;
    __m128i orig15 = x_15;
    __m128i t_0, t_1, t_2, t_3, t_4, t_5, t_6, t_7, t_8, t_9, t_10, t_11, t_12,
        t_13, t_14, t_15;

    uint32_t in12, in13;
    int      i;

    while (bytes >= 256) {
        const __m128i addv12 = _mm_set_epi64x(1, 0);
        const __m128i addv13 = _mm_set_epi64x(3, 2);
        __m128i       t12, t13;
        uint64_t      in1213;

        x_0  = orig0;
        x_1  = orig1;
        x_2  = orig2;
        x_3  = orig3;
        x_4  = orig4;
        x_5  = orig5;
        x_6  = orig6;
        x_7  = orig7;
        x_8  = orig8;
        x_9  = orig9;
        x_10 = orig10;
        x_11 = orig11;
        x_14 = orig14;
        x_15 = orig15;

        in12   = x[12];
        in13   = x[13];
        in1213 = ((uint64_t) in12) | (((uint64_t) in13) << 32);
        t12    = _mm_set1_epi64x(in1213);
        t13    = _mm_set1_epi64x(in1213);

        x_12 = _mm_add_epi64(addv12, t12);
        x_13 = _mm_add_epi64(addv13, t13);

        t12 = _mm_unpacklo_epi32(x_12, x_13);
        t13 = _mm_unpackhi_epi32(x_12, x_13);

        x_12 = _mm_unpacklo_epi32(t12, t13);
        x_13 = _mm_unpackhi_epi32(t12, t13);

        orig12 = x_12;
        orig13 = x_13;

        in1213 += 4;

        x[12] = in1213 & 0xFFFFFFFF;
        x[13] = (in1213 >> 32) & 0xFFFFFFFF;

        for (i = 0; i < ROUNDS; i += 2) {
            VEC4_QUARTERROUND(0, 4, 8, 12);
            VEC4_QUARTERROUND(1, 5, 9, 13);
            VEC4_QUARTERROUND(2, 6, 10, 14);
            VEC4_QUARTERROUND(3, 7, 11, 15);
            VEC4_QUARTERROUND(0, 5, 10, 15);
            VEC4_QUARTERROUND(1, 6, 11, 12);
            VEC4_QUARTERROUND(2, 7, 8, 13);
            VEC4_QUARTERROUND(3, 4, 9, 14);
        }

#define ONEQUAD_TRANSPOSE(A, B, C, D)                                     \
    {                                                                     \
        __m128i t0, t1, t2, t3;                                           \
                                                                          \
        x_##A = _mm_add_epi32(x_##A, orig##A);                            \
        x_##B = _mm_add_epi32(x_##B, orig##B);                            \
        x_##C = _mm_add_epi32(x_##C, orig##C);                            \
        x_##D = _mm_add_epi32(x_##D, orig##D);                            \
        t_##A = _mm_unpacklo_epi32(x_##A, x_##B);                         \
        t_##B = _mm_unpacklo_epi32(x_##C, x_##D);                         \
        t_##C = _mm_unpackhi_epi32(x_##A, x_##B);                         \
        t_##D = _mm_unpackhi_epi32(x_##C, x_##D);                         \
        x_##A = _mm_unpacklo_epi64(t_##A, t_##B);                         \
        x_##B = _mm_unpackhi_epi64(t_##A, t_##B);                         \
        x_##C = _mm_unpacklo_epi64(t_##C, t_##D);                         \
        x_##D = _mm_unpackhi_epi64(t_##C, t_##D);                         \
                                                                          \
        t0 = _mm_xor_si128(x_##A, _mm_loadu_si128((__m128i*) (m + 0)));   \
        _mm_storeu_si128((__m128i*) (c + 0), t0);                         \
        t1 = _mm_xor_si128(x_##B, _mm_loadu_si128((__m128i*) (m + 64)));  \
        _mm_storeu_si128((__m128i*) (c + 64), t1);                        \
        t2 = _mm_xor_si128(x_##C, _mm_loadu_si128((__m128i*) (m + 128))); \
        _mm_storeu_si128((__m128i*) (c + 128), t2);                       \
        t3 = _mm_xor_si128(x_##D, _mm_loadu_si128((__m128i*) (m + 192))); \
        _mm_storeu_si128((__m128i*) (c + 192), t3);                       \
    }

#define ONEQUAD(A, B, C, D) ONEQUAD_TRANSPOSE(A, B, C, D)

        ONEQUAD(0, 1, 2, 3);
        m += 16;
        c += 16;
        ONEQUAD(4, 5, 6, 7);
        m += 16;
        c += 16;
        ONEQUAD(8, 9, 10, 11);
        m += 16;
        c += 16;
        ONEQUAD(12, 13, 14, 15);
        m -= 48;
        c -= 48;

#undef ONEQUAD
#undef ONEQUAD_TRANSPOSE

        bytes -= 256;
        c += 256;
        m += 256;
    }
}
#undef VEC4_ROT
#undef VEC4_QUARTERROUND
#undef VEC4_QUARTERROUND_SHUFFLE