diff --git a/README.md b/README.md
index c14fd8f6..f8340b5c 100644
--- a/README.md
+++ b/README.md
@@ -740,9 +740,7 @@ Grouped in options:\
 [Valor Econômico](https://valor.globo.com)*
 ##### Chile
 [Diario Financiero](https://www.df.cl) -
-[El Mercurio](https://digital.elmercurio.com) -
-[El Mercurio de Valparaíso](https://www.mercuriovalpo.cl) -
-[La Estrella de Valparaíso](https://www.estrellavalpo.cl) -
+[El Mercurio (+ regional/opt-in to custom sites)](https://digital.elmercurio.com) -
 [La Segunda](https://digital.lasegunda.com) -
 [La Tercera](https://www.latercera.com)
 ##### Colombia
diff --git a/background.js b/background.js
index 0c90b494..9e461d05 100644
--- a/background.js
+++ b/background.js
@@ -750,8 +750,11 @@ ext_api.webRequest.onBeforeSendHeaders.addListener(function(details) {
     let custom_domain = urlHost(header_referer).replace(/^(www|m|account|amp|edition|eu)\./, '');
     if (custom_allow_cookies && !allow_cookies.includes(custom_domain))
       allow_cookies.push(custom_domain);
-    if (custom_block_regex)
+    if (custom_block_regex) {
+      if ((typeof custom_block_regex === 'string') && custom_block_regex.includes('{domain}'))
+        custom_block_regex = new RegExp(custom_block_regex.replace('{domain}', custom_domain.replace(/\./g, '\\.')));
       blockedRegexes[custom_domain] = custom_block_regex;
+    }
     if (custom_useragent) {
       if (custom_useragent === 'googlebot') {
         if (!use_google_bot.includes(custom_domain))
@@ -803,6 +806,13 @@ ext_api.webRequest.onBeforeSendHeaders.addListener(function(details) {
       var ch_media_domain = (matchUrlDomain('static-chmedia.ch', details.url) && ['script'].includes(details.type) && !matchUrlDomain(ch_media_domains, header_referer) && enabledSites.includes('nzz.ch'));
       if (ch_media_domain)
         ch_media_domains = customAddRules(ch_media_domains, true, blockedRegexes['nzz.ch'], 'googlebot');
+    } else if (header_referer_hostname.endsWith('.cl')) {
+      // block scripts for regional El Mercurio sites (opt-in to custom sites)
+      var cl_emol_region_domains = [];
+      var cl_emol_region_domain = (matchUrlDomain('impresa.soy-chile.cl', details.url) && ['xmlhttprequest'].includes(details.type) && !matchUrlDomain(cl_emol_region_domains, header_referer) && enabledSites.includes('elmercurio.com'));
+      if (cl_emol_region_domain) {
+        cl_emol_region_domains = customAddRules(cl_emol_region_domains, false, "(\\.{domain}\\/impresa\\/.+\\/assets\\/(vendor|\\d)\\.js|pram\\.pasedigital\\.cl\\/API\\/User\\/Status\\?)");
+	  }
     } else if (header_referer_hostname.endsWith('.de')) {
       // set googlebot-useragent for additional Funke sites (opt-in to custom sites)
       var de_funke_medien_domains = grouped_sites['###_de_funke_medien'];
@@ -1093,7 +1103,7 @@ if (matchUrlDomain(change_headers, details.url) && !['font', 'image', 'styleshee
         }
       }
     });
-  } else { //mercuriovalpo.cl, estrellavalpo.cl, lequipe.fr
+  } else { //El Mercurio Regionales, lequipe.fr
     ext_api.tabs.query({
       active: true,
       currentWindow: true
diff --git a/changelog.txt b/changelog.txt
index 649a99d0..b418fbc8 100644
--- a/changelog.txt
+++ b/changelog.txt
@@ -8,6 +8,7 @@ Add Het Belang van Limburg
 Add Het Nieuwsblad
 Add SlideShare
 Remove Scribd (fix obsolete)
+Fix El Mercurio (+ regional/opt-in to custom sites)
 Fix Telegraaf.nl
 
 * v2.7.0.0 (2022-05-22)
diff --git a/contentScript.js b/contentScript.js
index ef370b4a..f9194429 100644
--- a/contentScript.js
+++ b/contentScript.js
@@ -2352,7 +2352,7 @@ else if (matchDomain('lasegunda.com')) {
   }
 }
 
-else if (matchDomain(["mercuriovalpo.cl", "estrellavalpo.cl"])) {
+else if (window.location.hostname.endsWith('.cl') && document.querySelector('meta[property="og:image"][content*="://impresa.soy-chile.cl/"]')) {
   let content = document.querySelector('div.content');
   if (content)
     content.setAttribute('id', 'content_new');
diff --git a/manifest.json b/manifest.json
index ea6043cf..484c4ca4 100644
--- a/manifest.json
+++ b/manifest.json
@@ -207,7 +207,6 @@
         "*://*.esprit.presse.fr/*",
         "*://*.esquire.com/*",
         "*://*.estadao.com.br/*",
-        "*://*.estrellavalpo.cl/*",
         "*://*.estrepublicain.fr/*",
         "*://*.euobserver.com/*",
         "*://*.eurekareport.com.au/*",
@@ -389,7 +388,6 @@
         "*://*.medium.com/*",
         "*://*.mediuutiset.fi/*",
         "*://*.menshealth.com/*",
-        "*://*.mercuriovalpo.cl/*",
         "*://*.mercurynews.com/*",
         "*://*.mexiconewsdaily.com/*",
         "*://*.miamiherald.com/*",
@@ -677,6 +675,7 @@
         "*://*.prcdn.co/*",
         "*://*.repstatic.it/*",
         "*://*.sanoma-sndp.fi/*",
+        "*://*.soy-chile.cl/*",
         "*://*.static-chmedia.ch/*",
         "*://*.wallkit.net/*",
         "*://*.wsj.net/*",
diff --git a/sites.js b/sites.js
index 7d39c329..b4ceb3b1 100644
--- a/sites.js
+++ b/sites.js
@@ -384,16 +384,12 @@ var defaultSites = {
     allow_cookies: 1,
     block_regex: /(\.tinypass\.com\/|cdn\.cxense\.com\/|cdn\.ampproject\.org\/v\d\/amp-subscriptions-.+\.js)/
   },
-  "El Mercurio": {
+  "El Mercurio (+ regional/opt-in to custom sites)": {
     domain: "elmercurio.com",
     allow_cookies: 1,
     block_regex: /\.(elmercurio\.com|emol\.cl)\/(.+\/)?js\/(.+\/)?(modal|merPramV\d|PramModal\.min)\.js/,
     useragent: "googlebot"
   },
-  "El Mercurio de Valparaíso": {
-    domain: "mercuriovalpo.cl",
-    block_regex: /(.+\.mercuriovalpo\.cl\/impresa\/.+\/assets\/(vendor|\d)\.js|pram\.pasedigital\.cl\/API\/User\/Status\?)/
-  },
   "El Mundo": {
     domain: "elmundo.es",
     group_rule: "###_gr_es_unidad_domains"
@@ -916,10 +912,6 @@ var defaultSites = {
     allow_cookies: 1,
     block_regex: /(\.la-croix\.com\/build\/lacroix\/article.+\.js|cdn\.ampproject\.org\/v\d\/amp-access-.+\.js)/
   },
-  "La Estrella de Valparaíso": {
-    domain: "estrellavalpo.cl",
-    block_regex: /(\.mercuriovalpo\.cl\/impresa\/.+\/assets\/(vendor|\d)\.js|pram\.pasedigital\.cl\/API\/User\/Status\?)/
-  },
   "La Libre.be": {
     domain: "lalibre.be",
     allow_cookies: 1,